R&D > ACTIVITY        


   
































The pharmaceutical preparations research team is organized for the development of new medicament and medicine forms. With this development the analytic methods are determined for new medicaments. Stability tests are also accomplished at the same time according to ICH-Guidelines.

The pharmaceutical preparations research team is also interested in generic-products. Therefore, we compare dissolution tests.


* Specialized Field
1) Development of new formulation
  - New medicine form planning and physical characteristics test
(solubility, melting point, particle size, friability, etc.)
  - New special medicine forms research (Sustained-release-tablet)

2) Development of new medicament
  - Study of new medicament: Formulation development for the new medicaments such as oral dosage, Injectable formulation, etc.
  - Analytic method establishment for new medicaments
  - Stability test for IND- and NDA-data

3) Development of generic products
  - Comparison of dissolution test


Our goals are to invent new small molecules and development improved or novel processes for the efficient and cost-saving synthesis of valuable active pharmaceutical ingredients (API) and intermediates, and improvement studies on industrial production with BGMP compliance.
We will strive for new synthetic technology development of potential drug substances in the foreign market and on the chiral synthetic method development of optical active API and intermediate substances that are expected to have marketability in the future.
In addition, we are trying to focus on studying pharmaceutical peptides, which are potential new candidates for anti-cancer drugs.
* Specialized Field
1) Synthesis of pharmaceutical raw materials and research & development of the manufacturing process
  - Process development of APIs for new and generic drugs
  - Research synthesis process improvement for the cost reduction of
    existing pharmaceutical raw materials
  - Outstanding production and process optimization techniques
  - Studying pharmaceutical peptides
 
We can evaluate the efficacy of drugs and new compounds through various in vitro and in vivo models. In addition, we use genomic and proteomic methods as the best-known ways to identify targets and for identification of target molecules. We have various in vitro models which can evaluate candidate compounds for anti-cancer, anti-inflammation and anti-HBV drugs. There is also a lab animal facility which can be used for various in vivo experiments.
 
* Specialized Field
1) Development of new drugs and validation
  - Gene Cloning
  - Recombinant Proteins
  - Signal transduction mediate proteins
  - Deriving new drugs from natural substances
2) Pharmacology / Toxicology
  - Anti-cancer research
  - Anti-viral research
  - Anti-inflammatory research
  - Research of Alzheimer's disease